I have just started using the i2M with the following hardware :
MacBook Pro (i5) 8GB, RME Fireface UFX, Logic Studio 9, Apple Bluetooth Mouse
With the UFX is connected via USB, i2M (USB), and an iLok on the remaining USB port, the i2M is basically unusable (latency, glitches, missed notes etc.). Also, the bluetooth mouse stutters/ is unresponsive. I swapped the various devices between the ports but I couldn't achieve stability. Finally, I connected the Fireface UFX via firewire. The i2M is now usable! The mouse behaves.
Has anyone experienced similar issues?
It appears that there is a driver conflict or USB overload(?) when the audio interface (RME) is connected via USB.